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Kelly Butts, B.Sc.
Academic Information
2008-present, PhD student (in progress)
University of British Columbia (Neuroscience)
2004: Bachelor of Science
University of Edinburgh, Scotland (Pharmacology)
Research Interests
Kelly's research uses in vivo microdialysis to examine how stress system abnormalities can lead to alterations in neurotransmitter systems relevant to depression.
Specifically, she uses an animal model of prenatal alcohol exposure to understand whether hypothalamic-pituitary-adrenal abnormalities known to occur in these animals and in human patients with depression lead to direct changes in mesocortical dopaminergic neurotransmission. Alterations in the mesocortical dopamine system are associated with many of the behavioural manifestations of depression including executive dysfunction and dysregulation of emotion. A second line of research aims to directly examine the role of the glucocorticoid receptor in modulating the dopamine system through both neurochemical and behavioural examination.
Publications
Peer-reviewed
- Cousins DA, Butts K, Young AH (2009). Dopamine in Bipolar Disorder: from
Neurotransmission to Treatment. Bipolar Disorders. (Submitted December 2009).
Posters
- Butts K, Uban KA, Ahn S, Yu W, So K, Weinberg J, Young AH, Phillips AG (2009).
Stress-evoked dopamine release is altered in the medial prefrontal cortex of rats
prenatally exposed to alcohol: Implications for hypothalamic-pituitary-adrenal (HPA) axis dysregulation in depression. (Presentation at the May, 2009 3rd Annual Canadian Neuroscience Meeting, Vancouver, Canada).
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This page was last updated on 27 August 2009.
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